Post-operative complications of penetrating corneal keratoplasty in patients with anterior segment toxic syndrome secondary to cataract surgery

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Elen Nishimoto Nishi
Vagner Loduca Lima
Glaucia Luciano da Veiga
Luiz Antonio de Brito Martins

Abstract

Introduction: Toxic Anterior Segment Syndrome (TASS) after cataract surgery may cause severe corneal decompensation that compromises corneal transparency and may require penetrating corneal keratoplasty to improve visual acuity. Objective: We evaluated the postoperative complications of patients who underwent penetrating corneal transplantation for severe corneal decompensation secondary to TASS after cataract surgery, such as persistent epithelial defect, glaucoma, and primary and secondary transplant button failure. We will also evaluate pre- and postoperative visual acuity, graft survival time, and the presence of anterior chamber disorganization. Methods: Retrospective observational study in which a review of medical records of 9 patients diagnosed with TASS after cataract surgery who underwent penetrating corneal keratoplasty will occur. Results: In the present study all operated patients had glaucoma after penetrating corneal transplantation, and this presence of glaucoma was not correlated with graft survival time and with any other parameter evaluated. The presence of persistent epithelial defect correlated negatively with visual acuity. Conclusion: Postoperative complications of penetrating corneal transplantation in patients with TASS were frequent, such as glaucoma, primary and secondary button failure and persistent epithelial defect. The only complication that compromised visual acuity was the persistent epithelial defect. All patients evolved with glaucoma.

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How to Cite
Nishi, E. N. ., Lima, V. L. ., Veiga, G. L. da ., & Martins, L. A. de B. . (2020). Post-operative complications of penetrating corneal keratoplasty in patients with anterior segment toxic syndrome secondary to cataract surgery. ABCS Health Sciences, 45(Suppl.3), e020105. https://doi.org/10.7322/abcshs.2020S05.1852
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Original Articles

References

1. Miyake G, Ota I, Miyake K, Zako M, Iwaki M, Shibuya A. Late-onset toxic anterior segment syndrome. J Cataract Refract Surg. 2015;41(3):666-9. https://doi.org/10.1016/j.jcrs.2015.01.002

2. Holland SP, Morck DW, Lee TL. Update on toxic anterior segment syndrome. Curr Opin Ophthalmol. 2007;18(1):4-8. https://doi.org/10.1097/ICU.0b013e3280117d0c

3. Sengupta S, Chang DF, Gandhi R, Kenia H, Venkatesh R. Incidence and long-term outcomes of toxic anterior segment syndrome at Aravind Eye Hospital. J Cataract Refract Surg. 2011;37(9):1673-8. https://doi.org/10.1016/j.jcrs.2011.03.053

4. Yazgan S, Celik U, Ayar O, Ugurbas SH, Celik B, Akdemir MO, et al. The role of patient's systemic characteristics and plateletcrit in developing toxic anterior segment syndrome after uneventful phaco surgery: A case-control study. Int Ophthalmol. 2018;38(1):43-52. https://doi.org/10.1007/s10792-016-0418-x

5. Arslan OS, Unal M, Arici C, Görgün E, Yenerel M, Cicik E. Descemet-stripping automated endothelial keratoplasty in eyes with toxic anterior segment syndrome after cataract surgery. J Cataract Refract Surg. 2010;36(6):965-9. https://doi.org/10.1016/j.jcrs.2009.12.037

6. Sevimli N, Karadag R, Cakici O, Bayramlar H, Okumus S, Sari U. Toxic anterior segment syndrome following deep anterior lamellar keratoplasty. Arq Bras Oftalmol. 2016;79(5):330-2. https://doi.org/10.5935/0004-2749.20160094

7. Shouchane-Blum K, Dotan A, Bahar I. The evolution of toxic anterior segment syndrome. Curr Opin Ophthalmol. 2019;30(1):50-5. https://doi.org/10.1097/ICU.0000000000000540

8. Bodnar Z, Clouser S, Mamalis N. Toxic anterior segment syndrome: Update on the most common causes. J Cataract Refract Surg. 2012;38(11):1902-10. https://doi.org/10.1016/j.jcrs.2012.06.053

9. Park CY, Lee JK, Chuck RS. Toxic anterior segment syndrome-an updated review. BMC Ophthalmol. 2018;18(1):276. https://doi.org/10.1186/s12886-018-0939-3