Epidemiological profile of nosocomial urinary infection in university hospital of Campina Grande (PB)

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Ygor Paiva Schiel Baracuhy
Cátia Sueli de Sousa Eufrazino Gondin
Andréa Amorim Pereira Barros
Haysa Paiva Baracuhy
Verena Schiel Baracuhy

Abstract

Introduction: The urinary tract infection (UTI) is the most frequent nosocomial infection. Objective: This study aims to categorize and identify issues related to nosocomial urinary tract infection (NUTI) at the Hospital Universitário Alcides Carneiro (HUAC), in Campina Grande (PB), delineating a profile of patients with this diagnosis during hospitalization from January to July of 2012 in the wards hospital (general medicine, cardiology, endocrinology, pulmonology and infectious diseases). Methods: We analyzed 436 medical records pertaining to admissions. The research based on quantitative and qualitative data is characterized by a descriptive study. Variables examined included age, sex, ward, length of hospitalization, indwelling catheter (IC) and duration, diagnostic tests, evolution to NUTI, drugs used as initial empirical therapy, agents isolated from urine culture and antimicrobial susceptibility of isolated pathogens. Results: It was identified in the evolution to NUTI 12.61% of hospitalizations, predominantly among elderly patients and those with SVD, beyond the supremacy of Escherichia coli among pathogens and their rate of fluoroquinolone resistance in 50%. Conclusion: The strains of E. coli isolated showed sensitivity to cephalosporins 2nd and 3rd generations, amikacin and meropenem. The isolated strains of Klebsiella pneumoniae, second most common pathogen, were only sensitive to cefoxitin and meropenem. Fluoroquinolones were, in our research, the most prescribed as empiric therapy, which may explain the high rates of resistance encountered, making then unsuitable for use empirical treatment of new cases.

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How to Cite
Baracuhy, Y. P. S., Gondin, C. S. de S. E., Barros, A. A. P., Baracuhy, H. P., & Baracuhy, V. S. (2013). Epidemiological profile of nosocomial urinary infection in university hospital of Campina Grande (PB). ABCS Health Sciences, 38(3). https://doi.org/10.7322/abcshs.v38i3.20
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Original Articles

References

1. Cullen IM, Manecksha RP, McCullagh E, Ahmad S, O'Kelly F, Flynn RJ, et al. The changing pattern of antimicrobial resistance within 42 033 Escherichia coli isolates from nosocomial, community and urology patient-specific urinary tract infections, Dublin, 1999-2009. BJU Int. 2012;109(8):1198-206. http://dx.doi.org/10.1111/j.1464-410X.2011.10528.x

2. Brusaferro S, Regattin L, Silvestro A, Vidotto L. Incidence of hospitalacquired infection in Italian long-term-care facilities: a prospective six-munth surveillance. J Hosp Infec. 2006;63(2):211-5. http://dx.doi.org/10.1016/j.jhin.2006.01.012

3. Dias Neto JA, Silva LDM, Martins ACP, Tiraboschi RB, Domingos ALA, Suaid HJ, et al. Prevalence and bacterial susceptibility of hospital acquired urinary tract nfection. Acta Cir Bras. 2003;18(Suppl 5):36-8. http://dx.doi.org/10.1590/S0102-86502003001200013

4. Correia C, Costa E, Peres A, Alves A, Pombo G, Estevinho L. Etiologia das infecções do tracto urinário e sua susceptibilidade aos antimicrobianos. Acta Med Port. 2007;20:543-9.

5. Brasil. Ministério do Planejamento, Orçamento e Gestão. Instituto Brasileiro de Geografia e Estatística. Contagem Populacional. Disponível em: http://www.sidra.ibge.gov.br/. Acesso em: 10 out. 2011.

6. Foxman B. The epidemiology of urinary tract infection. Nat Rev Urol. 2010;7(12):653-60. http://dx.doi.org/10.1038/nrurol.2010.190

7. Avci M, Ozgenc O, Coskuner SA, Olut AI. Hospital acquired infections (HAI) in the elderly: comparison with the younger patients. Arch Gerontol Geriatr. 2012;54(1):247-50. http://dx.doi.org/10.1016/j.archger.2011.03.014

8. Eriksen HM, Koch P, Elstrom P, Nilsen RM, Harthug B, Aavitsland P. Healthcare-associeted infection among residents of long-term care facilities: a cohort and nested case-control study. J Hosp Infection. 2007;65(4):334-40. http://dx.doi.org/10.1016/j.jhin.2006.11.011

9. Lenz LL. Cateterismo vesical: cuidados, complicações e medidas preventivas. Arq Catarinenses Medicina. 2006;35(1):82-91.

10. Hooton TM, Bradley SF, Cardenas DD, Colgan R, Geerlings SE, Rice JC, et al. Diagnosis, prevention, and treatment of catheterassociated urinary tract infection in adults: 2009 International Clinical Practice Guildemines from the Infectious Diseases Society of America. Clin Infect Dis. 2010;50(5):625-63. http://dx.doi.org/10.1086/650482

11. Shigemura K, Tanaka K, Adachi M, Yamashita M, Arakawa S, Fujisawa M. Chronological change of antibiotic use and antibiotic resistance in Escherichia coli causing urinary tract infections. J Infect Chemother. 2011;17(5):646-51. http://dx.doi.org/10.1007/s10156-011-0241-2

12. Vilela APO. Prevalência anual e perfil de susceptibilidade de microrganismos isolados de infecções comunitárias e nosocomiais em hospital particular de Belo Horizonte - MG. Monografia [Especialização em Microbiologia] - Universidade Federal de Minas Gerais (UFMG). Belo Horizonte, 2009.

13. Soto SM, Smithson A, Horcaiada JP, Martinez JA, Mensa JP, Vila J. Implication of biofilm formation in the persistence of urinary tract infection caused by uropathogenic Escherichia coli. Clin Microbiol Infect. 2006;12(10):1034-6. http://dx.doi.org/10.1111/j.1469-0691.2006.01543.x

14. European Antimicrobial Resistance Surveillance System [internet]. Annual report 2008. Disponível em: http://www.ecdc.europa.eu/en/activities/surveillance/ears-net/documents/2008_earss_annual_report.pdf. Acesso em: 29 mar. 2013.

15. Pallett A, Hand K. Complicated urinary tract infections: practical solutions for the treatment of multiresistant gram-negative bacteria.