Antifungal resistance in opportunistic candidiasis: challenges and risks to global public health

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Published: Apr 25, 2025
DOI: https://doi.org/10.7322/abcshs.2025043.3071

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Nathalia da Rosa Coelho Martins
Laboratory of Antibiotics, Biochemistry, Education and Molecular Modeling, Universidade Federal Fluminense (UFF) – Niterói (RJ) Brazil /Program in Pathology, School of Medicine, UFF – Niterói (RJ), Brazil
https://orcid.org/0000-0001-6999-5585
Thais Dias Costa Almeida
Laboratory of Antibiotics, Biochemistry, Education and Molecular Modeling, Universidade Federal Fluminense (UFF) – Niterói (RJ) Brazil /Program in Pathology, School of Medicine, UFF – Niterói (RJ), Brazil
https://orcid.org/0000-0003-3315-6725
Aldo Rodrigues da Silva
Laboratory of Antibiotics, Biochemistry, Education and Molecular Modeling, Universidade Federal Fluminense (UFF) – Niterói (RJ) Brazil /Program in Pathology, School of Medicine, UFF – Niterói (RJ), Brazil
https://orcid.org/0000-0002-4083-7855
Norman Arthur Ratcliffe
Department of Biosciences, Swansea University (SW) – Swansea, United Kingdom
https://orcid.org/0000-0001-8538-0636
Helena Carla Caastro
Laboratory of Antibiotics, Biochemistry, Education and Molecular Modeling, Universidade Federal Fluminense (UFF) – Niterói (RJ) Brazil /Program in Pathology, School of Medicine, UFF – Niterói (RJ), Brazil
https://orcid.org/0000-0001-5283-1541

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How to Cite
Martins, N. da R. C., Almeida, T. D. C., Silva, A. R. da, Ratcliffe, N. A., & Caastro, H. C. (2025). Antifungal resistance in opportunistic candidiasis: challenges and risks to global public health. ABCS Health Sciences. https://doi.org/10.7322/abcshs.2025043.3071
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Author Biography

Nathalia da Rosa Coelho Martins, Laboratory of Antibiotics, Biochemistry, Education and Molecular Modeling, Universidade Federal Fluminense (UFF) – Niterói (RJ) Brazil /Program in Pathology, School of Medicine, UFF – Niterói (RJ), Brazil

Graduado em Ciências Biomédicas pela UNIAN (2018), com especializações em Análises Clínicas, Microbiologia e Segurança Alimentar. Desde minha graduação no Laboratório de Antibióticos, Bioquímica, Ensino e Modelagem Molecular (LABiEMol), tenho me engajado ativamente na academia. Concluí uma pós-graduação em Segurança Alimentar pela UCAM (2021) e obtive um mestrado em Patologia pelo Programa de Pós-Graduação em Patologia da UFF (2021), com uma dissertação intitulada "Avaliação In Silico do Perfil Toxicológico e Potencial Antifúngico Contra Candida spp. de Derivados de Quinona". Atualmente, estou cursando um doutorado no mesmo programa, com foco no potencial e perfil toxicológico de biomoléculas, derivados sintéticos e híbridos contra cepas *Candida*. No segundo semestre de 2024, concluí um estágio de pesquisa nos Estados Unidos na North Dakota State University (NDSU), financiado pela CAPES, onde avancei em análises toxicológicas in vitro e in silico de compostos antifúngicos candidatos em colaboração com o Departamento de Ciências Farmacêuticas.

References

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Hamburger FG, Gales AC, Colombo AL. Systematic Review of Candidemia in Brazil: Unlocking Historical Trends and Challenges in Conducting Surveys in Middle-Income Countries. Mycopathologia. 2024;189(4):60. https://doi.org/10.1007/s11046-024-00867-w

World Health Organization (WHO). WHO fungal priority pathogens list to guide research, development and public health action. Geneva: World Health Organization; 2022.